I recently came across this problem on a customer’s computer and tried everything I could find via Google. Naturally, none of the solutions worked. When you click on the icon to start Outlook, the window shows up briefly and then disappears, popping up that extremely meaningful message: Cannot Start Microsoft Office Outlook. Cannot Open the Outlook Window .
If you google this problem, one of the first sites that shows up with a solution is Microsoft’s site, so you assume that the solution must be a good one. Actually, it didn’t work for me. The Microsoft page is this one. The solutions that they give probably work in many cases, but I tried both of their solutions and I was still at the starting line.
The solution? simply run: outlook.exe /resetnavpane
basically, this is the same as deleting your profilename.xml in your user directory. It did the trick for me and if I can save someone the trouble of looking for that solution for hours.. then I’m happy!